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Oh, God! Book II is a 1980 American comedy film and a sequel to the film Oh, God! (1977). It was directed by Gilbert Cates, and stars George Burns, Suzanne Pleshette, David Birney and Louanne Sirota. Joyce Brothers and Hugh Downs also made cameo appearances in the film.

Oh, God! Book II was followed by Oh, God! You Devil (1984). Burns was the only cast member who appeared in more than one of the films.

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